产品货号：
Z28897
中文名称：
TRMT12抗体
英文名称：
Anti-TRMT12 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TRMT12 Antibody |
| 指标别名 | TYW2;TRM12;TYW2;tRNA wybutosine-synthesizing protein 2 homolog;Alpha-amino-alpha-carboxypropyl transferase TYW2;tRNA-yW-synthesizing protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | TRMT12 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TYW2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TYW2.The immunogen is located within the first 50 amino acids of TYW2. |
| 计算分子量 | 50kDa |
| 成分 | TYW2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TYW2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | TYW2 antibody can be stored at 4℃,stable for one year.As with all antibodies care should be taken to avoid repeated freeze thaw cycles.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | TYW2,also known as TRM12,is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process,thereby ensuring correct translation.TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed,and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26,suggesting that TYW2 may play a role in breast cancer. |
| Uniprot ID | Q53H54 |
| 基因名全称 | TRNA methyltransferase 12 homolog |
| 蛋白名全称 | TRNA methyltransferase 12 homolog |
| 推荐稀释比 | TYW2 antibody can be used for detection of TYW2 by Western blot at 0.5μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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